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DOCKING OF FTase INHIBITORS

The following FTase inhibitors were docked in the protein structure as seen in the computational methods section. Click on the bidimensional structure to display each complex.

Display the FTase - (S)-FPOH complex (S)-FPOH (6)

Display the FTase - BZA-2B complex

BZA-2B (10)

Display the FTase - SCH-44342 complex

SCH-44342 (14)

Display the FTase - fusidienol complex

Fusidienol (13)

Display the FTase - 10'-desmethoxystreptonigrin  complex

10'-desmethoxystreptonigrin (12)

Display the FTase - zaragozic acid complex

Zaragozic acid (11)

 

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